I understand what you're saying.

我明白你说的意思。

Yep.

是的。

Spare me nothing.

把一切都告诉我。

Just try to be patient.

尽量耐心一点。

Keep your chin up.

别灰心。

I must take issue with your over what you said at the meeting.

我要和你好好谈谈你在会上说的那些话。（take issue with someone: 对某人的观点提出异议。）